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Test Name: | MMR Immunohistochemistry |
Compliance: | FDA |
Test Description: | DNA mismatch repair (MMR) is an essential physiological process for correcting mutations occurring during DNA replication. Deficient MMR (dMMR) leads to increased tumour mutational burden, with a heightened risk of neoplasia. Demonstration of dMMR via the immunohistochemical assessment of MMR proteins is useful when screening for inherited cancer syndromes (especially Lynch syndrome) and for the prediction of clinical cancer response to conventional chemotherapy and novel immunotherapies. |
Methodology: | Immunohistochemistry |
Gene Name: | N/A |
Protein Name: | |
Specimen Requirements: | FFPE tissue unstained sections on coated slides (4µm) |
Storage Condition: | Ambient Temperature |
Turn Around Time: | 5 working days from day of specimen received |
OMIM: | |
Genetic Home Reference: | |
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Copyright © 2013 香港分子病理檢驗中心 Hong Kong Molecular Pathology Diagnostic Centre Limited (HKMPDC). All Rights Reserved.
Information Updated 1 July, 2023.
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